Subsystem Coverage Subsystem Category Distribution Subsystem Feature Counts
not in Subsystem total (3977) non-hypothetical (2023) hypothetical (1954)
in Subsystem total (3043) non-hypothetical (2885) hypothetical (158)
Cofactors, Vitamins, Prosthetic Groups, Pigments 385 / 4441
Cell Wall and Capsule 174 / 4441
Virulence, Disease and Defense 185 / 4441
Potassium metabolism 20 / 4441
Membrane Transport 191 / 4441
Nucleosides and Nucleotides 119 / 4441
Protein Metabolism 317 / 4441
Cell Division and Cell Cycle 43 / 4441
Motility and Chemotaxis 122 / 4441
Regulation and Cell signaling 130 / 4441
Fatty Acids, Lipids, and Isoprenoids 263 / 4441
Nitrogen Metabolism 58 / 4441
Stress Response 210 / 4441
Metabolism of Aromatic Compounds 123 / 4441
Amino Acids and Derivatives 583 / 4441
Sulfur Metabolism 86 / 4441
Phosphorus Metabolism 65 / 4441
Cofactors, Vitamins, Prosthetic Groups, Pigments (385)
Cell Wall and Capsule (174)
Capsular and extracellular polysacchrides (57)
Gram-Negative cell wall components (46)
Cell Wall and Capsule - no subcategory (71)
Gram-Positive cell wall components (0) Cell wall of Mycobacteria (0) Potassium metabolism (20)
Potassium metabolism - no subcategory (20)
Photosynthesis (0)
Light-harvesting complexes (0) Photosynthesis - no subcategory (0) Electron transport and photophosphorylation (0)
Membrane Transport (191)
Protein secretion system, Type II (25)
ABC transporters (50)
Protein secretion system, Type VII (Chaperone/Usher pathway, CU) (0) Protein secretion system, Type I (0) Protein secretion system, Type III (0) Uni- Sym- and Antiporters (0) Sugar Phosphotransferase Systems, PTS (0) Protein secretion system, Type VIII (Extracellular nucleation/precipitation pathway, ENP) (0) Iron acquisition and metabolism (12)
Siderophores (4)
Iron acquisition and metabolism - no subcategory (8)
Iron transpot (0) RNA Metabolism (185)
RNA processing and modification (152)
Transcription (32)
RNA Metabolism - no subcategory (1)
Nucleosides and Nucleotides (119)
Pyrimidines (29)
Purines (64)
Nucleosides and Nucleotides - no subcategory (17)
Detoxification (9)
Protein Metabolism (317)
Protein folding (39)
Selenoproteins (7)
Protein biosynthesis (194)
tRNA aminoacylation, Val (1) tRNA aminoacylation, Met (2) tRNA aminoacylation, Ile (1) tRNA aminoacylation, Arg (1) Translation initiation factors bacterial (6) Ribosome SSU bacterial (25) tRNA aminoacylation, Gly (2) tRNA aminoacylation, Ala (2) Ribosome activity modulation (1) tRNA aminoacylation, Trp (1) Ribosome biogenesis bacterial (14) Ribosome LSU bacterial (36) Programmed frameshift (2) tRNA aminoacylation, Cys (1) Translation termination factors bacterial (14) tRNA aminoacylation, His (1) Universal GTPases (18) tRNA aminoacylation, Asp and Asn (13) Translation elongation factors bacterial (7) tRNAs (21) tRNA aminoacylation, Lys (1) tRNA aminoacylation, Thr (1) tRNA aminoacylation, Pro (1) Translation elongation factor G family (2) tRNA aminoacylation, Glu and Gln (13) tRNA aminoacylation, Ser (1) tRNA aminoacylation, Tyr (1) tRNA aminoacylation, Leu (1) Glycyl-tRNA synthetase (2) tRNA aminoacylation, Phe (2) Protein processing and modification (34)
Protein degradation (43)
Regulation and Cell signaling (130)
DNA Metabolism (128)
Fatty Acids, Lipids, and Isoprenoids (263)
Nitrogen Metabolism (58)
Nitrogen Metabolism - no subcategory (58)
Denitrification (0) Stress Response (210)
Metabolism of Aromatic Compounds (123)
Amino Acids and Derivatives (583)
Sulfur Metabolism (86)
Inorganic sulfur assimilation (21)
Sulfur Metabolism - no subcategory (26)
Organic sulfur assimilation (39)
Phosphorus Metabolism (65)
Phosphorus Metabolism - no subcategory (65)
Carbohydrates (762)
Category all Amino Acids and Derivatives Carbohydrates Cell Division and Cell Cycle Cell Wall and Capsule Cofactors, Vitamins, Prosthetic Groups, Pigments DNA Metabolism Dormancy and Sporulation Fatty Acids, Lipids, and Isoprenoids Iron acquisition and metabolism Membrane Transport Metabolism of Aromatic Compounds Miscellaneous Motility and Chemotaxis Nitrogen Metabolism Nucleosides and Nucleotides Phages, Prophages, Transposable elements, Plasmids Phosphorus Metabolism Potassium metabolism Protein Metabolism Regulation and Cell signaling Respiration RNA Metabolism Secondary Metabolism Stress Response Sulfur Metabolism Virulence, Disease and Defense Subcategory all ABC transporters Alanine, serine, and glycine Amino Acids and Derivatives - no subcategory Aminosugars Arginine; urea cycle, polyamines Aromatic amino acids and derivatives Bacteriocins, ribosomally synthesized antibacterial peptides Biotin Branched-chain amino acids Capsular and extracellular polysacchrides Carbohydrates - no subcategory Cation transporters Cell Division and Cell Cycle - no subcategory Cell Wall and Capsule - no subcategory Central carbohydrate metabolism CO2 fixation Coenzyme A Cofactors, Vitamins, Prosthetic Groups, Pigments - no subcategory Cold shock Detoxification Di- and oligosaccharides DNA Metabolism - no subcategory DNA recombination DNA repair DNA replication DNA uptake, competence Dormancy and Sporulation - no subcategory Electron accepting reactions Electron donating reactions Fatty acids Fatty Acids, Lipids, and Isoprenoids - no subcategory Fermentation Flagellar motility in Prokaryota Folate and pterines Glutamine, glutamate, aspartate, asparagine; ammonia assimilation Gram-Negative cell wall components Heat shock Histidine Metabolism Inorganic sulfur assimilation Invasion and intracellular resistance Iron acquisition and metabolism - no subcategory Isoprenoids Lipoic acid Lysine, threonine, methionine, and cysteine Membrane Transport - no subcategory Metabolism of Aromatic Compounds - no subcategory Metabolism of central aromatic intermediates Miscellaneous - no subcategory Monosaccharides NAD and NADP Nitrogen Metabolism - no subcategory Nucleosides and Nucleotides - no subcategory One-carbon Metabolism Organic acids Organic sulfur assimilation Osmotic stress Oxidative stress Peripheral pathways for catabolism of aromatic compounds Periplasmic Stress Phages, Prophages Phospholipids Phosphorus Metabolism - no subcategory Plant Alkaloids Plant Hormones Plant-Prokaryote DOE project Polysaccharides Potassium metabolism - no subcategory Programmed Cell Death and Toxin-antitoxin Systems Proline and 4-hydroxyproline Protein and nucleoprotein secretion system, Type IV Protein biosynthesis Protein degradation Protein folding Protein processing and modification Protein secretion system, Type II Protein secretion system, Type V Protein secretion system, Type VI Protein translocation across cytoplasmic membrane Purines Pyridoxine Pyrimidines Quinone cofactors Quorum sensing and biofilm formation Regulation and Cell signaling - no subcategory Resistance to antibiotics and toxic compounds Respiration - no subcategory Riboflavin, FMN, FAD RNA Metabolism - no subcategory RNA processing and modification Selenoproteins Siderophores Stress Response - no subcategory Sugar alcohols Sulfur Metabolism - no subcategory Tetrapyrroles Transcription TRAP transporters Subsystem Role Features Cofactors, Vitamins, Prosthetic Groups, Pigments Biotin Biotin synthesis cluster Competence protein F homolog, phosphoribosyltransferase domain fig|32008.146.peg.3159 Cofactors, Vitamins, Prosthetic Groups, Pigments Biotin Biotin synthesis cluster Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) fig|32008.146.peg.3058 , fig|32008.146.peg.4767 , fig|32008.146.peg.6005 Cofactors, Vitamins, Prosthetic Groups, Pigments Biotin Biotin synthesis cluster 8-amino-7-oxononanoate synthase (EC 2.3.1.47) fig|32008.146.peg.3057 Cofactors, Vitamins, Prosthetic Groups, Pigments Biotin Biotin synthesis cluster Dethiobiotin synthetase (EC 6.3.3.3) fig|32008.146.peg.3056 Cofactors, Vitamins, Prosthetic Groups, Pigments Biotin Biotin synthesis cluster Biotin synthase (EC 2.8.1.6) fig|32008.146.peg.3055 Cofactors, Vitamins, Prosthetic Groups, Pigments Biotin Biotin synthesis cluster Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) fig|32008.146.peg.256 , fig|32008.146.peg.837 , fig|32008.146.peg.1603 , fig|32008.146.peg.1985 , fig|32008.146.peg.2746 , fig|32008.146.peg.3460 , fig|32008.146.peg.5030 , fig|32008.146.peg.6106 , fig|32008.146.peg.6455 , fig|32008.146.peg.6640 , fig|32008.146.peg.6730 Cofactors, Vitamins, Prosthetic Groups, Pigments Biotin Biotin synthesis cluster Biotin synthesis protein BioC fig|32008.146.peg.3160 Cofactors, Vitamins, Prosthetic Groups, Pigments Biotin Biotin synthesis cluster 3-ketoacyl-CoA thiolase (EC 2.3.1.16) fig|32008.146.peg.1875 , fig|32008.146.peg.3064 , fig|32008.146.peg.3285 , fig|32008.146.peg.6265 , fig|32008.146.peg.6272 Cofactors, Vitamins, Prosthetic Groups, Pigments Biotin Biotin synthesis cluster tRNA (cytidine(34)-2'-O)-methyltransferase (EC 2.1.1.207) fig|32008.146.peg.3158 Cofactors, Vitamins, Prosthetic Groups, Pigments Biotin Biotin synthesis cluster ATPase component BioM of energizing module of biotin ECF transporter fig|32008.146.peg.6091 Cofactors, Vitamins, Prosthetic Groups, Pigments Biotin Biotin biosynthesis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) fig|32008.146.peg.3058 , fig|32008.146.peg.4767 , fig|32008.146.peg.6005 Cofactors, Vitamins, Prosthetic Groups, Pigments Biotin Biotin biosynthesis 8-amino-7-oxononanoate synthase (EC 2.3.1.47) fig|32008.146.peg.3057 Cofactors, Vitamins, Prosthetic Groups, Pigments Biotin Biotin biosynthesis Dethiobiotin synthetase (EC 6.3.3.3) fig|32008.146.peg.3056 Cofactors, Vitamins, Prosthetic Groups, Pigments Biotin Biotin biosynthesis Biotin synthase (EC 2.8.1.6) fig|32008.146.peg.3055 Cofactors, Vitamins, Prosthetic Groups, Pigments Biotin Biotin biosynthesis Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) fig|32008.146.peg.256 , fig|32008.146.peg.837 , fig|32008.146.peg.1603 , fig|32008.146.peg.1985 , fig|32008.146.peg.2746 , fig|32008.146.peg.3460 , fig|32008.146.peg.5030 , fig|32008.146.peg.6106 , fig|32008.146.peg.6455 , fig|32008.146.peg.6640 , fig|32008.146.peg.6730
Cofactors, Vitamins, Prosthetic Groups, Pigments (385)
Cell Wall and Capsule (174)
Virulence, Disease and Defense (185)
Potassium metabolism (20)
Photosynthesis (0)
Miscellaneous (101)
Phages, Prophages, Transposable elements, Plasmids (8)
Membrane Transport (191)
Iron acquisition and metabolism (12)
RNA Metabolism (185)
Nucleosides and Nucleotides (119)
Protein Metabolism (317)
Cell Division and Cell Cycle (43)
Motility and Chemotaxis (122)
Regulation and Cell signaling (130)
Secondary Metabolism (6)
DNA Metabolism (128)
Nitrogen Metabolism (58)
Dormancy and Sporulation (2)
Respiration (163)
Stress Response (210)
Metabolism of Aromatic Compounds (123)
Amino Acids and Derivatives (583)
Sulfur Metabolism (86)
Phosphorus Metabolism (65)
Carbohydrates (762)
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